I've been using the Thirdsphere Hosting service for just over a year now. While Thirdsphere have provided superb uptime and decent support, they also include a unique ecommerce service which has proved to be very valuable to me.
It's called the Automation Station and allows you to set up a complete business selling digital or intangible items such as software or pdf files which can be paid for and automatically downloaded by the customer. You can set up the system to use Paypal, 2Checkout or your own merchant account to accept payments easily.
Other features included in the Automation Station include a built in autoresponder system for followup sales plus even an affiliate sytem so other webmasters can sign up and sell your digital products for a standard or customized commission.
The cost of $24.95 per month might usually seem a bit steep for a 30 gb shared hosting account, but the inclusion of the AutomationStation at no extra cost makes this service a bargain that no other web host I know of provides.
If setting up an automated business selling digital goods is of interest to you I encourage you to take a look at the Thirdsphere Automation Station today.